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Viagra

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General Information about Viagra

Viagra, also known by its generic name sildenafil, is a medication commonly used to treat erectile dysfunction in men. It is often the first treatment tried for this condition, as well as for pulmonary arterial hypertension (PAH). In this article, we will delve into what Viagra is, how it works, and its benefits and potential risks.

Viagra was originally developed in 1989 by pharmaceutical company Pfizer as a treatment for high blood pressure and angina. However, during clinical trials, it was discovered to have a significant effect on erectile dysfunction. It was approved by the U.S. Food and Drug Administration (FDA) in 1998 and since then has been widely used to treat both erectile dysfunction and PAH.

Erectile dysfunction, also known as impotence, is the inability to achieve and maintain an erection sufficient for sexual intercourse. It is a common condition affecting millions of men worldwide, particularly those over the age of 40. Causes of erectile dysfunction can vary, including physical factors such as diabetes, high blood pressure, and hormonal imbalances, as well as psychological factors such as stress, depression, and anxiety.

PAH, on the other hand, is a condition in which the blood pressure in the arteries that supply the lungs is abnormally high. This makes it difficult for the heart to pump blood through the lungs, leading to shortness of breath, fatigue, and chest pain. PAH is a rare condition, affecting about 15 to 50 people per million worldwide. It mostly occurs in women aged 20 to 40, although men can also be affected.

Viagra works by increasing blood flow to the penis, which is necessary for an erection to occur. It belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These drugs work by inhibiting the enzyme that breaks down a chemical called cyclic guanosine monophosphate (cGMP). cGMP is responsible for relaxing the smooth muscles in the penis, allowing more blood to flow in and creating an erection. Viagra does not cause an erection; it only helps to maintain one when there is sexual stimulation.

When used to treat PAH, Viagra works by relaxing the blood vessels in the lungs, making it easier for the heart to pump blood through them. This helps to reduce the symptoms of PAH and improve exercise capacity.

Viagra is available in three different dosages: 25mg, 50mg, and 100mg tablets. The recommended starting dose for erectile dysfunction is 50mg, taken one hour before sexual activity. The dose can be adjusted based on individual response. The recommended dose for PAH is 5 or 20mg taken three times a day, about four to six hours apart.

One of the main benefits of Viagra is its high success rate. Studies have shown that it can improve erectile function in about 70% of men with erectile dysfunction. It is also generally well-tolerated, with only mild side effects reported such as headache, flushing, and indigestion. However, in rare cases, it can cause serious side effects such as priapism (a prolonged and painful erection) and sudden hearing loss. It is important to consult a doctor before using Viagra, especially if you have any underlying medical conditions or are taking other medications.

In conclusion, Viagra is a highly effective and safe medication for treating erectile dysfunction and PAH. It has been a game-changer for many men, allowing them to regain their sexual prowess and enjoy a better quality of life. However, it should only be used under the supervision of a doctor, and it is crucial to understand and be aware of potential risks and side effects.

Viagra Dosage and Price

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